The Texas Department of State Health Services on Thursday unveiled a public service announcement with Perry, who's a nurse, and agency director Dr. Kyle Janek.
The 30-second announcement features Janek warning that flu cases can be severe and even fatal. The wife of Gov. Rick Perry says people with the flu should not wait for symptoms to get severe before consulting a doctor.
The PSA closes with the phrase: "Protect yourself and your fellow Texans."
Health officials say the level of flu-like illness is classified as "high" in Texas. This year's vaccine includes protection against H1N1, known as swine flu.